Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Special issue | Vol 54, No. 1, 2001, pp.43-47
Published online, 1st January, 1970
DOI: 10.3987/COM-00-S(I)7
Cascading Single-step Stereoselective Construction of the α-Alloyohimbine Framework: A New Synthesis of (-)-Nitraraine

Hideki Sakagami and Kunio Ogasawara*

*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan

Abstract

(—)-Nitraraine and its 10-methoxy -analogue having an α-alloyohimbine framework have been constructed stereoselectively in a cascading single step sequence from chiral mono-substituted N-2-(3-indolyl)ethyltetrahydro-pyridine precursors under the Heck reaction conditions.