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Communication | Special issue | Vol 54, No. 1, 2001, pp.93-99
Published online, 1st January, 1970
DOI: 10.3987/COM-00-S(I)61
Convergent Strategy for Synthesizing Polycyclic Ether Marine Toxins: Synthesis of the ABCDE Ring Fragment of Ciguatoxin CTX3C

Megumi Maruyama, Kenji Maeda, Tohru Oishi, Hiroki Oguri, and Masahiro Hirama*

*Department of Chemistry, Graduate School of Science, Tohoku University, Aobayama, Sendai 980-8578, Japan


The ABCDE ring fragment of CTX3C, the most important member of the ciguatoxin family, was concisely synthesized by extensive use of ring-closing olefin metathesis.