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Communication | Special issue | Vol 54, No. 2, 2001, pp.639-646
Published online, 1st January, 1970
DOI: 10.3987/COM-00-S(I)106
Structure of Sanggenon O, a Diels-Alder Type Adduct Derived from a Chalcone and a Dehydroprenylated Sanggenon-Type Flavanone from Morus cathayana

Ya-Qin Shi, Toshio Fukai, and Taro Nomura*

*Faculty of Pharmaceutical Sciences, Toho University, 2-2-1 Miyama, Funabashi, Chiba 274-8510, Japan


The structure of sanggenon O, which was isolated from the Chinese crude drug “Sag-bai-pi” and the root bark of Chinese mulberry tree (Morus cathayana), was revised based on its spectral and chemical evidences. The compound is regarded as a Diels-Alder type adduct produced with a chalcone and a 6-dehydroprenylflavanone forming an ether linkage between the 2’- and 3-positions and its absolute configuration was 2S,3R,3”S,4”R,5”S.