Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 53, No. 5, 2000, pp.1065-1074
Published online, 1st January, 1970
DOI: 10.3987/COM-00-8858
[4+2] Cycloaddition Reaction of 3-Hydrazono-1,1,1-trifluoro-2-alkanones to 4,5-Bis(trifluoromethyl)pyridazines

Yasuhiro Kamitori*

*Department of Chemical Science and Engineering, Faculty of Engineering, Kobe University, Kobe 657-8501, Japan


Mechanisms for the reaction of 3-hydrazono-1,1,1-trifluoro-2- alkanons (1) to 4,5-bis(trifluoromethyl)pyridazines (2) in the presence of TFA are discussed on the basis of the 6-31G* level ab initio calculations. The results indicate a concerted [4+2] cycloaddition reaction of protonated 1 to be a key step for this reaction.