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Note | Regular issue | Vol 53, No. 6, 2000, pp.1343-1350
Published online, 1st January, 1970
DOI: 10.3987/COM-00-8856
Three New Diterpene Alkaloids from Spiraea japonica

Bin-Gui Wang, Ling Li, Xiao-Sheng Yang, Zhi-He Chen, and Xiao-Jiang Hao*

*Laboratory of Phytochemistry, Kunming Institute of Botany, The Chinese Academy of Sciences, Kunming 650204, China


Chemical investigation of the basic fraction from the roots of Spiraea japonica var. acuta has resulted in the isolation of three new diterpene alkaloids, spiramines X (1), Y (2) and Z (3), along with five known compounds, spiradine F (4), and spiramines A, B, P (5), and U (6). The structures of 1-3 were determined by spectral and chemical methods. Antiplatelet aggregation activities of compounds (1- 6) were tested.