Natural Products with Heterocyclic Ring System

Synthesis

New Heterocyclic Natural Products

Updated: 7 November, 2019

This journal will list the new natural products with a heterocyclic ring system, collected from current chemical literature, whose synthesis has been established.

79 data found. 1 - 30 listed Next Last
Polyketides

Putaminoxin

C12H20O3 = 212
Tetrahedron 2019, 75, 689
D. Dickmann, M. Diekmann, C. Holec, J. Pietruszka
DOI: 10.1016/j.tet.2018.12.027
CrossRef
chiral
racemic
Notes:
Polyketides

Cardiobutanolide

C13H16O6 = 268
Tetrahedron Lett. 2019, 60, 684
I. Kovačević, M. Popsavin, M. V. Rodić, V. Kojić, V. Popsavin
DOI: 10.1016/j.tetlet.2019.01.059
CrossRef
chiral
racemic
Notes:
Polyketides

Berkeleylactone F

C16H28O5 = 300
Tetrahedron Lett. 2019, 60, 504
M. S. Reddy, G. Manikanta, P. R. Krishna
DOI: 10.1016/j.tetlet.2019.01.017
CrossRef
chiral
racemic
Notes:
Polyketides

Sekothrixide

C28H50O6 = 482
J. Org. Chem. 2019, 84, 1553
D. Katsumi, K. Nakasone, N. Terayama, E. Yasui, M. Mizukami, M. Miyashita, S. Nagumo
DOI: 10.1021/acs.joc.8b03006
CrossRef
chiral
racemic
Notes:
Polyketides

Borrelidin

C28H43NO6 = 489
Bull. Chem. Soc. Japan 2019, 92, 359
V. Gembus, L. Karmazin, D. Uguen, T. Zoller
DOI: 10.1246/bcsj.20180292
CrossRef
chiral
racemic
Notes: formal synthesis
Aromatics

Nyingchinoid D

C17H22O2 = 258
Angew. Chem. Int. Ed. 2019, 58, 2791
J. D. Hart, L. Burchill, A. J. Day C. G. Newton, C. J. Sumby D. M. Huang, J. H. George
DOI: 10.1002/anie.201981713
CrossRef
chiral
racemic
Notes:
Aromatics

Nyingchinoid A

C17H22O4 = 290
Angew. Chem. Int. Ed. 2019, 58, 2791
J. D. Hart, L. Burchill, A. J. Day C. G. Newton, C. J. Sumby D. M. Huang, J. H. George
DOI: 10.1002/anie.201981713
CrossRef
chiral
racemic
Notes:
Aromatics

Nyingchinoid B

C17H22O4 = 290
Angew. Chem. Int. Ed. 2019, 58, 2791
J. D. Hart, L. Burchill, A. J. Day C. G. Newton, C. J. Sumby D. M. Huang, J. H. George
DOI: 10.1002/anie.201981713
CrossRef
chiral
racemic
Notes:
Aromatics

Cannabinol, ∆⁹-Tetrahydro-,

C21H30O2 = 314
Org. Lett. 2019, 21, 1212
A. Ametovski, D. W. Lupton
DOI: 10.1021/acs.orglett.9b00198
CrossRef
chiral
racemic
Notes:
Aromatics

Balsaminone A

C21H12O5 = 344
Synlett 2019, 30, 325
S.-K. A. Daley, N. K. Downer-Riley
DOI: 10.1055/s-0037-1611975
CrossRef
chiral
racemic
Notes:
Aromatics

Myxocoumarin B

C19H25NO5 = 347
Org. Biomol. Chem. 2019, 17, 1966
J. I. Müller, K. Kusserow, G. Hertrampf, A. Pavic, J. Nikodinovic-Runic, T. A. M. Gulder
DOI: 10.1039/C8OB02273A
CrossRef
chiral
racemic
Notes:
Aromatics

Integrin

C21H20O6 = 368
Eur. J. Org. Chem. 2019, , 1571
R. J. Smith, R. L. Bower, S. A. Ferguson, R. J. Rosengren, G. M. Cook, B. C. Hawkins
DOI: 10.1002/ejoc.201801751
CrossRef
chiral
racemic
Notes:
Aromatics

Rasumatranin D

C24H25O4 = 380
Angew. Chem. Int. Ed. 2019, 58, 2791
J. D. Hart, L. Burchill, A. J. Day C. G. Newton, C. J. Sumby D. M. Huang, J. H. George
DOI: 10.1002/anie.201981713
CrossRef
chiral
racemic
Notes: Revised structure
Aromatics

Integrin, Oxyisocyclo-

C21H20O7 = 384
Eur. J. Org. Chem. 2019, , 1571
R. J. Smith, R. L. Bower, S. A. Ferguson, R. J. Rosengren, G. M. Cook, B. C. Hawkins
DOI: 10.1002/ejoc.201801751
CrossRef
chiral
racemic
Notes:
Terpenes

Vibralactone

C12H16O3 = 208
Angew. Chem. Int. Ed. 2019, 58, 1724
S. K. Nistanaki, L. A. Boralsky, R. D. Pan, H. M. Nelson
DOI: 10.1002/anie.201981713
CrossRef
chiral
racemic
Notes:
Terpenes

Englerin A

C26H34O6 = 442
Eur. J. Org. Chem. 2019, , 1027
C. Reagan, G. Trevitt, K. Tchabanenko
DOI: 10.1002/ejoc.201801544
CrossRef
chiral
racemic
Notes:
Alkaloids

Supinidine

C8H13NO = 139
Eur. J. Org. Chem. 2019, , 1830
C. Dehoux, T. Castellan, M. Enel, C. André-Barrès, S. Mirval, F. Becq, S. Ballereau, Y. Génisson
DOI: 10.1002/ejoc.201900071
CrossRef
chiral
racemic
Notes:
Alkaloids

No Name

C8H13NO2 = 155
Eur. J. Org. Chem. 2019, , 1830
C. Dehoux, T. Castellan, M. Enel, C. André-Barrès, S. Mirval, F. Becq, S. Ballereau, Y. Génisson
DOI: 10.1002/ejoc.201900071
CrossRef
chiral
racemic
Notes:
Alkaloids

Subulacine

C8H13NO2 = 155
Eur. J. Org. Chem. 2019, , 1830
C. Dehoux, T. Castellan, M. Enel, C. André-Barrès, S. Mirval, F. Becq, S. Ballereau, Y. Génisson
DOI: 10.1002/ejoc.201900071
CrossRef
chiral
racemic
Notes:
Alkaloids

Nicotine

C10H14N2 = 162
Org. Lett. 2019, 21, 705
E. D. Castillo, K. Muñiz
DOI: 10.1021/acs.orglett.8b03909
CrossRef
chiral
racemic
Notes:
Alkaloids

Trasalpinecine

C8H15NO3 = 173
Eur. J. Org. Chem. 2019, , 1830
C. Dehoux, T. Castellan, M. Enel, C. André-Barrès, S. Mirval, F. Becq, S. Ballereau, Y. Génisson
DOI: 10.1002/ejoc.201900071
CrossRef
chiral
racemic
Notes: revised structure
Alkaloids

Australine

C8H15NO4 = 189
Eur. J. Org. Chem. 2019, , 1077
I.-S. Myeong, W.-H. Ham
DOI: 10.1002/ejoc.201801552
CrossRef
chiral
racemic
Notes:
Alkaloids

Cep-210

C11H20N3O = 210
Org. Lett. 2019, 21, 780
M. Adachi, T. Miyasaka, Y. Kudo, K. Sugimoto, M. Yotsu-Yamashita, T. Nishikawa
DOI: 10.1021/acs.orglett.8b04043
CrossRef
chiral
racemic
Notes:
Alkaloids

Glycozolicine

C14H13NO = 211
Tetrahedron 2019, 75, 874
B. k. g. Bhatthula, J. r. Kanchani, V. r. Arava, M. C. S. Subha
DOI: 10.1016/j.tet.2019.01.003
CrossRef
chiral
racemic
Notes:
Alkaloids

Glycozoline

C14H13NO = 211
Tetrahedron 2019, 75, 874
B. k. g. Bhatthula, J. r. Kanchani, V. r. Arava, M. C. S. Subha
DOI: 10.1016/j.tet.2019.01.003
CrossRef
chiral
racemic
Notes:
Alkaloids

Murrayafoline A

C14H13NO = 211
Tetrahedron 2019, 75, 874
B. k. g. Bhatthula, J. r. Kanchani, V. r. Arava, M. C. S. Subha
DOI: 10.1016/j.tet.2019.01.003
CrossRef
chiral
racemic
Notes:
Alkaloids

Cep-212

C11H22N3O = 212
Org. Lett. 2019, 21, 780
M. Adachi, T. Miyasaka, Y. Kudo, K. Sugimoto, M. Yotsu-Yamashita, T. Nishikawa
DOI: 10.1021/acs.orglett.8b04043
CrossRef
chiral
racemic
Notes:
Alkaloids

Thiasporine A

C10H8N2O2S = 220
Tetrahedron Lett. 2019, 60, 610
I. C. Vaaland, E. Lindbäck, M. O. Sydnes
DOI: 10.1016/j.tetlet.2019.01.038
CrossRef
chiral
racemic
Notes:
Alkaloids

Mukolidine

C14H11NO2 = 225
Tetrahedron 2019, 75, 874
B. k. g. Bhatthula, J. r. Kanchani, V. r. Arava, M. C. S. Subha
DOI: 10.1016/j.tet.2019.01.003
CrossRef
chiral
racemic
Notes:
Alkaloids

Murrayanine

C14H11NO2 = 225
Tetrahedron 2019, 75, 874
B. k. g. Bhatthula, J. r. Kanchani, V. r. Arava, M. C. S. Subha
DOI: 10.1016/j.tet.2019.01.003
CrossRef
chiral
racemic
Notes:
79 data found. 1 - 30 listed Next Last