Natural Products with Heterocyclic Ring System

Structure

New Heterocyclic Natural Products

Updated: 26 June, 2015

This journal will list the new natural products with a heterocyclic ring system, collected from current chemical literature, whose structure has been established.

223 data found. 211 - 223 listedFirst Previous
Alkaloids

Pyrrolocin A

C27H39NO5 = 457
J. Nat. Prod. 2014, 77, 2537
R. C. Jadulco, M. Koch, T. B. Kakule, E. W. Schmidt, A. Orendt, H. He, J. E. Janso, G. T. Carter, E. C. Larson, C. Pond, T. K. Matainaho, L. R. Barrows
DOI: 10.1021/np500617u
CrossRef
[ NS ] NRRL 50135
[ mp ]
[ bp ]
[ α ] D + 56.1   [ MeOH ]
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ] antimycobacterial activity
Alkaloids

Plakinamine O

C31H50N2O2 = 482
J. Nat. Prod. 2014, 77, 2475
S. N. Sunassee, T. Ransom, C. J. Henrich, J. A. Beutler, D. G. Covell, J. B. McMahon, K. R. Gustafson
DOI: 10.1021/np500556t
CrossRef
[ NS ] Corticium niger
[ mp ]
[ bp ]
[ α ] D + 17.5   [ MeOH ]
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ] growth inhibit activity
Alkaloids

Cephatonine-2-O-β-D-glucopyranoside

C26H35NO10 = 521
Tetrahedron 2014, 70, 8893
Y.-H. Li, H.-M. Li, Y. Li, J. He, X. Deng, L.-Y. Peng, L.-H. Gao, Q.-S. Zhao, R.-T. Li, X.-D. Wu
DOI: 10.1016/j.tet.2014.09.088
CrossRef
[ NS ] Sinomenium acutum
[ mp ]
[ bp ]
[ α ] D - 55.3   [ MeOH ]
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ]
Alkaloids

Pyrapaxilline

C37H47NO5 = 585
J. Antibiot. 2014, 67, 787
C. Matsui, Y. Ikeda, H. Iinuma, N. Kushida, T. Kunisada, S. Simizu, K. Umezawa
DOI: 10.1038/ja.2014.63
CrossRef
[ NS ] Eupenicillium shearii
[ mp ]
[ bp ]
[ α ] D – 11   [ MeOH ]
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ] inhibition of LPS-induced NO production
Alkaloids

Sallisonine C

C37H40N2O7 = 624
Tetrahedron 2014, 70, 8893
Y.-H. Li, H.-M. Li, Y. Li, J. He, X. Deng, L.-Y. Peng, L.-H. Gao, Q.-S. Zhao, R.-T. Li, X.-D. Wu
DOI: 10.1016/j.tet.2014.09.088
CrossRef
[ NS ] Sinomenium acutum
[ mp ]
[ bp ]
[ α ] D + 3.5   [ MeOH ]
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ]
Alkaloids

Sallisonine B

C38H40N2O7 = 636
Tetrahedron 2014, 70, 8893
Y.-H. Li, H.-M. Li, Y. Li, J. He, X. Deng, L.-Y. Peng, L.-H. Gao, Q.-S. Zhao, R.-T. Li, X.-D. Wu
DOI: 10.1016/j.tet.2014.09.088
CrossRef
[ NS ] Sinomenium acutum
[ mp ]
[ bp ]
[ α ] D + 31.3   [ CHCl3 ]
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ] ability to inhibit NO production of LPS-stimulated RAW264.7 macrophages
Alkaloids

Sallisonine A

C38H42N2O7 = 638
Tetrahedron 2014, 70, 8893
Y.-H. Li, H.-M. Li, Y. Li, J. He, X. Deng, L.-Y. Peng, L.-H. Gao, Q.-S. Zhao, R.-T. Li, X.-D. Wu
DOI: 10.1016/j.tet.2014.09.088
CrossRef
[ NS ] Sinomenium acutum
[ mp ]
[ bp ]
[ α ] D + 69.4   [ CHCl3 ]
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ] cytotoxicity against HL-60, SMMC-7721, A-549, MCF-7, SW480
Miscellaneous

Onionin A2

C9H16O2S2 = 220
Chem. Pharm. Bull. 2014, 62, 1141
T. Nohara, Y. Fujiwara, R. Kudo, K. Yamaguchi, T. Ikeda, K. Murakami, M. Ono, T. Kajimoto, M. Takeya
DOI: 10.1248/cpb.c14-00461
CrossRef
[ NS ] Allium cepa and Aliium fistulosum
[ mp ]
[ bp ]
[ α ] D + 16.0   [ CHCl3 ]
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ]
Miscellaneous

Onionin A3

C9H16O2S2 = 220
Chem. Pharm. Bull. 2014, 62, 1141
T. Nohara, Y. Fujiwara, R. Kudo, K. Yamaguchi, T. Ikeda, K. Murakami, M. Ono, T. Kajimoto, M. Takeya
DOI: 10.1248/cpb.c14-00461
CrossRef
[ NS ] Allium cepa and Aliium fistulosum
[ mp ]
[ bp ]
[ α ] D + 12.5   [ CHCl3 ]
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ]
Miscellaneous

MKN-349A, 5,5’-Epoxy-

C22H34N4O5 = 434
Helv. Chim. Acta 2014, 97, 1564
Z.-F. Zhou, X.-H. Yang, H.-L. Liu, Y.-C. Gu, B.-P. Ye, Y.-W. Guo
DOI: 10.1002/hlca.201400062
CrossRef
[ NS ] Penicillium species GD6
[ mp ]
[ bp ]
[ α ] D – 62.8   [ MeOH ]
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ]
Miscellaneous

Pashinintide A

C28H35N7O6 = 565
Tetrahedron Lett. 2014, 55, 6231
L. Cai, M. Zhao, S. Liu, T. Yin, H. Zhou, J. Dong, Y. Yang, Z. Ding
DOI: 10.1016/j.tetlet.2014.09.063
CrossRef
[ NS ] Pyrus pashia Buch.-Ham. ex D. Don
[ mp ] > 370 ℃
[ bp ]
[ α ] D – 10.9   [ MeOH ]
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ]
Miscellaneous

Pashinintide B

C34H50N8O9 = 714
Tetrahedron Lett. 2014, 55, 6231
L. Cai, M. Zhao, S. Liu, T. Yin, H. Zhou, J. Dong, Y. Yang, Z. Ding
DOI: 10.1016/j.tetlet.2014.09.063
CrossRef
[ NS ] Pyrus pashia Buch.-Ham. ex D. Don
[ mp ] 270.9 - 272.3 ℃
[ bp ]
[ α ] D – 12.0   [ Py. ]
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ]
Miscellaneous

Jatrophidine

C42H62N10O9 = 850
Phytochemistry 2014, 107, 91
W. F. Altei, D. G. Picchi, B. M. Abissi, G. M. Giesel, O. Flausino Jr., M. Reboud-Ravaux, H. Verli, E. Crusca Jr., E. R. Silveira, E. M. Cilli, V. S. Bolzani
DOI: 10.1016/j.phytochem.2014.08.006
CrossRef
[ NS ] Jatropha curcas
[ mp ]
[ bp ]
[ α ] D - 68.0   [ MeOH ]
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ] protease inhibition activity
223 data found. 211 - 223 listedFirst Previous