HETEROCYCLES

An International Journal for Reviews and Communications in Heterocyclic Chemistry
Web Edition ISSN: 1881-0942
Published online by The Japan Institute of Heterocyclic Chemistry

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Search65,753 Compounds

Nomenclature:

The natural products are listed under the name used in the original literature.

The abbreviations:

The following abbreviations have been used:

• act:
• biological activity

• cd:
• circular dichroism

• Cnmr:
• 13C-nuclear magnetic resonance spectrum

• Hnmr:
• 1H-nuclear magnetic resonance spectrum

• ir:
• infrared spectrum

• mass:
• mass spectrum

• syn:
• total synthesis

• uv:
• ultraviolet spectrum

Journal:

This database lists the natural products with heterocyclic ring system whose synthesis has been determined since 1975. The journals which have been covered are as follows:

Angew. Chem. Int. Ed. Engl.
Angew. Chem. Int. Ed.
Bull. Chem. Soc. Japan
Chem. and Ind.
Chem. Ber.
J. Chem. Soc., Chem. Commun.
Chem. Commun.
Chem. Eur. J.
Chemistry Lett.
Chem. Pharm. Bull.
Coll. Czech. Chem. Commun.
Eur. J. Inorg. Chem.
Eur. J. Org. Chem.
Experientia
Helv. Chim. Acta
Heterocycles
J. Am. Chem. Soc.
J. Antibiot.
J. Chem. Soc., Perkin Trans. 1
J. Heterocycl. Chem.
J. Med. Chem.
J. Nat. Prod.
J. Org. Chem.
J. Pharm. Sci.
Liebigs Ann. Chem.
Monatsh. Chem.
Org. Lett.
Phytochemistry
Planta medica
Synlett
Synth. Commun.
Synthesis
Tetrahedron
Tetrahedron Asymmetry
Tetrahedron Lett.
Yakugaku Zasshi

Editor:

Editor:
Kunio Ogasawara

Associate Editors:
Toshio Honda
Yoshiharu Iwabuchi

This journal will list the new natural products with a heterocyclic ring system, collected from current chemical literature, whose structure has been established.

• Search by Group: AllPolyketidesAromaticsTerpenesSteroidsAlkaloidsAntibioticsMiscellaneous
• Search by Journal: Chem. Pharm. Bull.Helv. Chim. ActaHeterocyclesJ. Antibiot.J. Nat. Prod.J. Org. Chem.Org. Biomol. Chem.Org. Lett.Phytochem. Lett.PhytochemistryPlanta medicaTetrahedronTetrahedron Lett.
• Year: 2014201420142014201420142014201420142014201420142014
• Vol: 6297896777791216107107807055
• No: 11111111112143, 4421, 22  1744-4745-48

Polyketides

No Name

C12H14O5 = 238

Tetrahedron Lett. 2014, 55, 6530

D.-B. Hu, W.-X. Li, Z.-Z. Zhao, T. Feng, R.-H. Yin, Z.-H. Li, J.-K. Liu, H.-J. Zhu

DOI: 10.1016/j.tetlet.2014.09.132

CrossRef

[	NS	]	Junghuhnianitida
[	mp	]
[	bp	]
[	α	] D	– 8.3   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Polyketides

No Name

C13H16O5 = 252

Tetrahedron Lett. 2014, 55, 6530

D.-B. Hu, W.-X. Li, Z.-Z. Zhao, T. Feng, R.-H. Yin, Z.-H. Li, J.-K. Liu, H.-J. Zhu

DOI: 10.1016/j.tetlet.2014.09.132

CrossRef

[	NS	]	Junghuhnianitida
[	mp	]
[	bp	]
[	α	] D	– 7.6   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Polyketides

Amdigenol G

C60H101O25NaS = 1276

Tetrahedron Lett. 2014, 55, 6319

T. Inuzuka, K. Yamada, D. Uemura

DOI: 10.1016/j.tetlet.2014.09.094

CrossRef

[	NS	]	Amphidinium species
[	mp	]
[	bp	]
[	α	] D	– 5.3   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	inhibitory activity against N-type Ca2+ channel-opening

Polyketides

Amdigenol E

C82H137O37NaS = 1768

Tetrahedron Lett. 2014, 55, 6319

T. Inuzuka, K. Yamada, D. Uemura

DOI: 10.1016/j.tetlet.2014.09.094

CrossRef

[	NS	]	Amphidinium species
[	mp	]
[	bp	]
[	α	] D	– 6.4   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	inhibitory activity against N-type Ca2+ channel-opening

Aromatics

Bacillcoumacin A

C16H21NO5 = 307

Tetrahedron Lett. 2014, 55, 6286

J. Bai, D. Liu, S. Yu, P. Proksch, W. Lin

DOI: 10.1016/j.tetlet.2014.09.100

CrossRef

[	NS	]	Bacillus species
[	mp	]
[	bp	]
[	α	] D	– 95.6   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Aromatics

Bacillcoumacin G

C20H24N2O5 = 372

Tetrahedron Lett. 2014, 55, 6286

J. Bai, D. Liu, S. Yu, P. Proksch, W. Lin

DOI: 10.1016/j.tetlet.2014.09.100

CrossRef

[	NS	]	Bacillus species
[	mp	]
[	bp	]
[	α	] D	– 53.6   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	inhibitory activity against NO production

Aromatics

Bacillcoumacin D

C20H25NO7 = 391

Tetrahedron Lett. 2014, 55, 6286

J. Bai, D. Liu, S. Yu, P. Proksch, W. Lin

DOI: 10.1016/j.tetlet.2014.09.100

CrossRef

[	NS	]	Bacillus species
[	mp	]
[	bp	]
[	α	] D	– 62.0   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Aromatics

Bacillcoumacin B

C20H28N2O7 = 408

Tetrahedron Lett. 2014, 55, 6286

J. Bai, D. Liu, S. Yu, P. Proksch, W. Lin

DOI: 10.1016/j.tetlet.2014.09.100

CrossRef

[	NS	]	Bacillus species
[	mp	]
[	bp	]
[	α	] D	– 82.0   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Aromatics

Bacillcoumacin C

C21H28N2O7 = 420

Tetrahedron Lett. 2014, 55, 6286

J. Bai, D. Liu, S. Yu, P. Proksch, W. Lin

DOI: 10.1016/j.tetlet.2014.09.100

CrossRef

[	NS	]	Bacillus species
[	mp	]
[	bp	]
[	α	] D	– 86.8   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Aromatics

Bacillcoumacin E

C21H27NO7S = 437

Tetrahedron Lett. 2014, 55, 6286

J. Bai, D. Liu, S. Yu, P. Proksch, W. Lin

DOI: 10.1016/j.tetlet.2014.09.100

CrossRef

[	NS	]	Bacillus species
[	mp	]
[	bp	]
[	α	] D	– 105.0   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Aromatics

Bacillcoumacin F

C21H27NO7S = 437

Tetrahedron Lett. 2014, 55, 6286

J. Bai, D. Liu, S. Yu, P. Proksch, W. Lin

DOI: 10.1016/j.tetlet.2014.09.100

CrossRef

[	NS	]	Bacillus species
[	mp	]
[	bp	]
[	α	] D	– 100.4   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Terpenes

Holophyllin A

C20H30O5 = 350

Tetrahedron Lett. 2014, 55, 6504

C. S. Kim, B. Shin, O. W. Kwon, S. Y. Kim, S. U. Choi, D.-C. Oh, K. H. Kim, K. R. Lee

DOI: 10.1016/j.tetlet.2014.10.030

CrossRef

[	NS	]	Abies holophylla
[	mp	]
[	bp	]
[	α	] D	– 12.3   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	inhibitory activity against NO production

Terpenes

Pahangensin D

C40H52O6 = 628

Tetrahedron Lett. 2014, 55, 6163

Y. Sivasothy, C. C. K. Zachariah, K. H. Leong, S. K. S. John, H. Ibrahim, K. Awang

DOI: 10.1016/j.tetlet.2014.08.115

CrossRef

[	NS	]	Alpinia pahangensis Ridley
[	mp	]
[	bp	]
[	α	] D
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Alkaloids

No Name

C10H5NO3 = 187

Tetrahedron Lett. 2014, 55, 6530

D.-B. Hu, W.-X. Li, Z.-Z. Zhao, T. Feng, R.-H. Yin, Z.-H. Li, J.-K. Liu, H.-J. Zhu

DOI: 10.1016/j.tetlet.2014.09.132

CrossRef

[	NS	]	Junghuhnianitida
[	mp	]
[	bp	]
[	α	] D
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	cytotoxic activity

Alkaloids

Vincamajorine A

C20H20N2O2 = 320

Tetrahedron Lett. 2014, 55, 6490

Z.-J. Zhang, J. Yang, J. He, X.-D. Wu, L.-D. Shao, Y. Li, S.-X. Huang, R.-T. Li, Q.-S. Zhao

DOI: 10.1016/j.tetlet.2014.10.011

CrossRef

[	NS	]	Vinca major
[	mp	]
[	bp	]
[	α	] D	– 13.04   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Alkaloids

Vincamajorine B

C20H22N2O2 = 322

Tetrahedron Lett. 2014, 55, 6490

Z.-J. Zhang, J. Yang, J. He, X.-D. Wu, L.-D. Shao, Y. Li, S.-X. Huang, R.-T. Li, Q.-S. Zhao

DOI: 10.1016/j.tetlet.2014.10.011

CrossRef

[	NS	]	Vinca major
[	mp	]
[	bp	]
[	α	] D	– 114.40   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Alkaloids

Strychnine-chloromethochloride, Deoxy-iso-

C22H24N2OCl = 367.5

Tetrahedron Lett. 2014, 55, 6538

Y.-S. Shi, Y.-B. Liu, S.-G. Ma, L. Li, J. Qu,Y. Li, S.-S. Yu

DOI: 10.1016/j.tetlet.2014.09.127

CrossRef

[	NS	]	Strychnos nux-vomica
[	mp	]
[	bp	]
[	α	] D	+ 45.98   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Alkaloids

Stryvomicine A

C23H27N2O3 = 379

Tetrahedron Lett. 2014, 55, 6538

Y.-S. Shi, Y.-B. Liu, S.-G. Ma, L. Li, J. Qu,Y. Li, S.-S. Yu

DOI: 10.1016/j.tetlet.2014.09.127

CrossRef

[	NS	]	Strychnos nux-vomica
[	mp	]
[	bp	]
[	α	] D	– 34.10   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Alkaloids

Colubrine-chloromethochloride, α-

C23H26N2O3Cl = 413.5

Tetrahedron Lett. 2014, 55, 6538

Y.-S. Shi, Y.-B. Liu, S.-G. Ma, L. Li, J. Qu,Y. Li, S.-S. Yu

DOI: 10.1016/j.tetlet.2014.09.127

CrossRef

[	NS	]	Strychnos nux-vomica
[	mp	]
[	bp	]
[	α	] D	– 78.5   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Alkaloids

Colubrine-chloromethochloride, β-

C23H26N2O3Cl = 413.5

Tetrahedron Lett. 2014, 55, 6538

Y.-S. Shi, Y.-B. Liu, S.-G. Ma, L. Li, J. Qu,Y. Li, S.-S. Yu

DOI: 10.1016/j.tetlet.2014.09.127

CrossRef

[	NS	]	Strychnos nux-vomica
[	mp	]
[	bp	]
[	α	] D	– 105.0   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Miscellaneous

Pashinintide A

C28H35N7O6 = 565

Tetrahedron Lett. 2014, 55, 6231

L. Cai, M. Zhao, S. Liu, T. Yin, H. Zhou, J. Dong, Y. Yang, Z. Ding

DOI: 10.1016/j.tetlet.2014.09.063

CrossRef

[	NS	]	Pyrus pashia Buch.-Ham. ex D. Don
[	mp	]	> 370 ℃
[	bp	]
[	α	] D	– 10.9   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Miscellaneous

Pashinintide B

C34H50N8O9 = 714

Tetrahedron Lett. 2014, 55, 6231

L. Cai, M. Zhao, S. Liu, T. Yin, H. Zhou, J. Dong, Y. Yang, Z. Ding

DOI: 10.1016/j.tetlet.2014.09.063

CrossRef

[	NS	]	Pyrus pashia Buch.-Ham. ex D. Don
[	mp	]	270.9 - 272.3 ℃
[	bp	]
[	α	] D	– 12.0   [ Py. ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

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