HETEROCYCLES

An International Journal for Reviews and Communications in Heterocyclic Chemistry
Web Edition ISSN: 1881-0942
Published online by The Japan Institute of Heterocyclic Chemistry

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Search65,753 Compounds

Nomenclature:

The natural products are listed under the name used in the original literature.

The abbreviations:

The following abbreviations have been used:

• act:
• biological activity

• cd:
• circular dichroism

• Cnmr:
• 13C-nuclear magnetic resonance spectrum

• Hnmr:
• 1H-nuclear magnetic resonance spectrum

• ir:
• infrared spectrum

• mass:
• mass spectrum

• syn:
• total synthesis

• uv:
• ultraviolet spectrum

Journal:

This database lists the natural products with heterocyclic ring system whose synthesis has been determined since 1975. The journals which have been covered are as follows:

Angew. Chem. Int. Ed. Engl.
Angew. Chem. Int. Ed.
Bull. Chem. Soc. Japan
Chem. and Ind.
Chem. Ber.
J. Chem. Soc., Chem. Commun.
Chem. Commun.
Chem. Eur. J.
Chemistry Lett.
Chem. Pharm. Bull.
Coll. Czech. Chem. Commun.
Eur. J. Inorg. Chem.
Eur. J. Org. Chem.
Experientia
Helv. Chim. Acta
Heterocycles
J. Am. Chem. Soc.
J. Antibiot.
J. Chem. Soc., Perkin Trans. 1
J. Heterocycl. Chem.
J. Med. Chem.
J. Nat. Prod.
J. Org. Chem.
J. Pharm. Sci.
Liebigs Ann. Chem.
Monatsh. Chem.
Org. Lett.
Phytochemistry
Planta medica
Synlett
Synth. Commun.
Synthesis
Tetrahedron
Tetrahedron Asymmetry
Tetrahedron Lett.
Yakugaku Zasshi

Editor:

Editor:
Kunio Ogasawara

Associate Editors:
Toshio Honda
Yoshiharu Iwabuchi

This journal will list the new natural products with a heterocyclic ring system, collected from current chemical literature, whose structure has been established.

• Search by Group: AllPolyketidesAromaticsTerpenesSteroidsAlkaloidsAntibioticsMiscellaneous
• Search by Journal: Chem. Pharm. Bull.Helv. Chim. ActaHeterocyclesJ. Antibiot.J. Nat. Prod.J. Org. Chem.Org. Biomol. Chem.Org. Lett.Phytochem. Lett.PhytochemistryPlanta medicaTetrahedronTetrahedron Lett.
• Year: 2014201420142014201420142014201420142014201420142014
• Vol: 6297896777791216107107807055
• No: 11111111112143, 4421, 22  1744-4745-48

Polyketides

Brevisulcatic Acid-4

C49H70O15 = 898

Org. Lett. 2014, 16, 5850

R. Suzuki, R. Irie, Y. Harntaweesup, K. Tachibana, P. T. Holland, D. T. Harwood, F. Shi, V. Beuzenberg, Y. Itoh, S. Pascal, P. J. B. Edwards, M. Satake

DOI: 10.1021/ol502700h

CrossRef

[	NS	]	Karenia brevisulcata
[	mp	]
[	bp	]
[	α	] D	+ 3.0   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Polyketides

Brevisulcatic Acid-1

C49H72O16 = 916

Org. Lett. 2014, 16, 5850

R. Suzuki, R. Irie, Y. Harntaweesup, K. Tachibana, P. T. Holland, D. T. Harwood, F. Shi, V. Beuzenberg, Y. Itoh, S. Pascal, P. J. B. Edwards, M. Satake

DOI: 10.1021/ol502700h

CrossRef

[	NS	]	Karenia brevisulcata
[	mp	]
[	bp	]
[	α	] D
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Aromatics

Saffloflavoneside A

C21H18O9 = 414

Org. Lett. 2014, 16, 5714

J. He, Y.-N. Yang, J. Jiang, Z.-M. Feng, P.-C. Zhang

DOI: 10.1021/ol502789x

CrossRef

[	NS	]	Carthamus tinctorius
[	mp	]
[	bp	]
[	α	] D	- 54.2   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	inhibitory activity against PC12 cell damage induced by rotenone

Aromatics

Saffloflavoneside B

C21H18O9 = 414

Org. Lett. 2014, 16, 5714

J. He, Y.-N. Yang, J. Jiang, Z.-M. Feng, P.-C. Zhang

DOI: 10.1021/ol502789x

CrossRef

[	NS	]	Carthamus tinctorius
[	mp	]
[	bp	]
[	α	] D	- 76.6   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	inhibitory activity against PC12 cell damage induced by rotenone

Aromatics

Rubialatin B

C27H20O7 = 456

Org. Lett. 2014, 16, 5576

S.-M. Zhao, Z. Wang, G.-Z. Zeng, W.-W. Song, X.-Q. Chen, X.-N. Li, N.-H. Tan

DOI: 10.1021/ol502603f

CrossRef

[	NS	]	Rubia alata
[	mp	]	204 - 206 ℃
[	bp	]
[	α	] D
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	cytotoxic activity

Aromatics

Delitschiapyrone A

C24H26O9 = 458

Org. Lett. 2014, 16, 5944

J.-G. Luo, X.-B. Wang, Y.-M. Xu, J. M. U’Ren, A. E. Arnold, L.-Y. Kong, A. A. L. Gunatilaka

DOI: 10.1021/ol502973c

CrossRef

[	NS	]	Delitschia species FL1581
[	mp	]
[	bp	]
[	α	] D	+ 121.0   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	cytotoxic activity

Aromatics

Rubialatin A

C27H20O8 = 472

Org. Lett. 2014, 16, 5576

S.-M. Zhao, Z. Wang, G.-Z. Zeng, W.-W. Song, X.-Q. Chen, X.-N. Li, N.-H. Tan

DOI: 10.1021/ol502603f

CrossRef

[	NS	]	Rubia alata
[	mp	]	272 - 274 ℃
[	bp	]
[	α	] D
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	cytotoxic activity
	Notes:		racemic compound

Alkaloids

Alstoscholarisine A

C19H24N2O = 296

Org. Lett. 2014, 16, 5808

X.-W. Yang, C.-P. Yang, L.-P. Jiang, X.-J. Qin, Y.-P. Liu, Q.-S. Shen, Y.-B. Chen, X.-D. Luo

DOI: 10.1021/ol5029223

CrossRef

[	NS	]	Alstonia scholaris
[	mp	]	151 - 152 ℃
[	bp	]
[	α	] D	- 184.6   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	promoting effect on adult neuronal stem cell proliferation

Alkaloids

Alstoscholarisine E

C19H24N2O = 296

Org. Lett. 2014, 16, 5808

X.-W. Yang, C.-P. Yang, L.-P. Jiang, X.-J. Qin, Y.-P. Liu, Q.-S. Shen, Y.-B. Chen, X.-D. Luo

DOI: 10.1021/ol5029223

CrossRef

[	NS	]	Alstonia scholaris
[	mp	]	138 - 140 ℃
[	bp	]
[	α	] D	- 340.7   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	promoting effect on adult neuronal stem cell proliferation

Alkaloids

Alstoscholarisine D

C20H24N2O3 = 340

Org. Lett. 2014, 16, 5808

X.-W. Yang, C.-P. Yang, L.-P. Jiang, X.-J. Qin, Y.-P. Liu, Q.-S. Shen, Y.-B. Chen, X.-D. Luo

DOI: 10.1021/ol5029223

CrossRef

[	NS	]	Alstonia scholaris
[	mp	]
[	bp	]
[	α	] D	- 148.5   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	promoting effect on adult neuronal stem cell proliferation

Alkaloids

Alstoscholarisine B

C21H26N2O3 = 354

Org. Lett. 2014, 16, 5808

X.-W. Yang, C.-P. Yang, L.-P. Jiang, X.-J. Qin, Y.-P. Liu, Q.-S. Shen, Y.-B. Chen, X.-D. Luo

DOI: 10.1021/ol5029223

CrossRef

[	NS	]	Alstonia scholaris
[	mp	]	168 - 169 ℃
[	bp	]
[	α	] D	- 162.3   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	promoting effect on adult neuronal stem cell proliferation

Alkaloids

Alstoscholarisine C

C21H26N2O3 = 354

Org. Lett. 2014, 16, 5808

X.-W. Yang, C.-P. Yang, L.-P. Jiang, X.-J. Qin, Y.-P. Liu, Q.-S. Shen, Y.-B. Chen, X.-D. Luo

DOI: 10.1021/ol5029223

CrossRef

[	NS	]	Alstonia scholaris
[	mp	]	98 - 101 ℃
[	bp	]
[	α	] D	- 213.3   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	promoting effect on adult neuronal stem cell proliferation

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