HETEROCYCLES

An International Journal for Reviews and Communications in Heterocyclic Chemistry
Web Edition ISSN: 1881-0942
Published online by The Japan Institute of Heterocyclic Chemistry

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Search65,753 Compounds

Nomenclature:

The natural products are listed under the name used in the original literature.

The abbreviations:

The following abbreviations have been used:

• act:
• biological activity

• cd:
• circular dichroism

• Cnmr:
• 13C-nuclear magnetic resonance spectrum

• Hnmr:
• 1H-nuclear magnetic resonance spectrum

• ir:
• infrared spectrum

• mass:
• mass spectrum

• syn:
• total synthesis

• uv:
• ultraviolet spectrum

Journal:

This database lists the natural products with heterocyclic ring system whose synthesis has been determined since 1975. The journals which have been covered are as follows:

Angew. Chem. Int. Ed. Engl.
Angew. Chem. Int. Ed.
Bull. Chem. Soc. Japan
Chem. and Ind.
Chem. Ber.
J. Chem. Soc., Chem. Commun.
Chem. Commun.
Chem. Eur. J.
Chemistry Lett.
Chem. Pharm. Bull.
Coll. Czech. Chem. Commun.
Eur. J. Inorg. Chem.
Eur. J. Org. Chem.
Experientia
Helv. Chim. Acta
Heterocycles
J. Am. Chem. Soc.
J. Antibiot.
J. Chem. Soc., Perkin Trans. 1
J. Heterocycl. Chem.
J. Med. Chem.
J. Nat. Prod.
J. Org. Chem.
J. Pharm. Sci.
Liebigs Ann. Chem.
Monatsh. Chem.
Org. Lett.
Phytochemistry
Planta medica
Synlett
Synth. Commun.
Synthesis
Tetrahedron
Tetrahedron Asymmetry
Tetrahedron Lett.
Yakugaku Zasshi

Editor:

Editor:
Kunio Ogasawara

Associate Editors:
Toshio Honda
Yoshiharu Iwabuchi

This journal will list the new natural products with a heterocyclic ring system, collected from current chemical literature, whose structure has been established.

• Search by Group: AllPolyketidesAromaticsTerpenesSteroidsAlkaloidsAntibioticsMiscellaneous
• Search by Journal: Chem. Pharm. Bull.Helv. Chim. ActaHeterocyclesJ. Antibiot.J. Nat. Prod.J. Org. Chem.Org. Biomol. Chem.Org. Lett.Phytochem. Lett.PhytochemistryPlanta medicaTetrahedronTetrahedron Lett.
• Year: 2014201420142014201420142014201420142014201420142014
• Vol: 6297896777791216107107807055
• No: 11111111112143, 4421, 22  1744-4745-48

Terpenes

Swielimonoid E

C43H56O19 = 876

J. Nat. Prod. 2014, 77, 2367

Y.-B. Cheng, Y.-T. Chien, J.-C. Lee, C.-K. Tseng, H.-C. Wang, I-W. Lo, Y.-H. Wu, S.-Y. Wang, Y.-C. Wu, F.-R. Chang

DOI: 10.1021/np5002829

CrossRef

[	NS	]	Swietenia macrophylla
[	mp	]
[	bp	]
[	α	] D	- 61   [ CH2Cl2 ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Terpenes

Bistenuifolin E

C48H62O15 = 878

J. Nat. Prod. 2014, 77, 2444

J.-H. Yang, W.-G. Wang, X. Du, F. He, H.-B. Zhang, X.-N. Li, Y. Li, J.-X. Pu, H.-D. Sun

DOI: 10.1021/np5005196

CrossRef

[	NS	]	Isodon tenuifolius
[	mp	]
[	bp	]
[	α	] D	- 12   [ CHCl3/MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Terpenes

Bistenuifolin C

C48H64O16 = 896

J. Nat. Prod. 2014, 77, 2444

J.-H. Yang, W.-G. Wang, X. Du, F. He, H.-B. Zhang, X.-N. Li, Y. Li, J.-X. Pu, H.-D. Sun

DOI: 10.1021/np5005196

CrossRef

[	NS	]	Isodon tenuifolius
[	mp	]
[	bp	]
[	α	] D	- 71   [ acetone ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Terpenes

Bistenuifolin F

C48H68O16 = 900

J. Nat. Prod. 2014, 77, 2444

J.-H. Yang, W.-G. Wang, X. Du, F. He, H.-B. Zhang, X.-N. Li, Y. Li, J.-X. Pu, H.-D. Sun

DOI: 10.1021/np5005196

CrossRef

[	NS	]	Isodon tenuifolius
[	mp	]	177 - 178 ℃
[	bp	]
[	α	] D	- 64   [ Acetone ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Terpenes

Swielimonoid F

C44H56O20 = 904

J. Nat. Prod. 2014, 77, 2367

Y.-B. Cheng, Y.-T. Chien, J.-C. Lee, C.-K. Tseng, H.-C. Wang, I-W. Lo, Y.-H. Wu, S.-Y. Wang, Y.-C. Wu, F.-R. Chang

DOI: 10.1021/np5002829

CrossRef

[	NS	]	Swietenia macrophylla
[	mp	]
[	bp	]
[	α	] D	- 121   [ CH2Cl2 ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Terpenes

Swielimonoid C

C45H58O20 = 918

J. Nat. Prod. 2014, 77, 2367

Y.-B. Cheng, Y.-T. Chien, J.-C. Lee, C.-K. Tseng, H.-C. Wang, I-W. Lo, Y.-H. Wu, S.-Y. Wang, Y.-C. Wu, F.-R. Chang

DOI: 10.1021/np5002829

CrossRef

[	NS	]	Swietenia macrophylla
[	mp	]
[	bp	]
[	α	] D	- 270   [ CH2Cl2 ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Terpenes

Swielimonoid D

C45H58O20 = 918

J. Nat. Prod. 2014, 77, 2367

Y.-B. Cheng, Y.-T. Chien, J.-C. Lee, C.-K. Tseng, H.-C. Wang, I-W. Lo, Y.-H. Wu, S.-Y. Wang, Y.-C. Wu, F.-R. Chang

DOI: 10.1021/np5002829

CrossRef

[	NS	]	Swietenia macrophylla
[	mp	]
[	bp	]
[	α	] D	+ 5   [ CH2Cl2 ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Terpenes

Bistenuifolin D

C50H66O16 = 922

J. Nat. Prod. 2014, 77, 2444

J.-H. Yang, W.-G. Wang, X. Du, F. He, H.-B. Zhang, X.-N. Li, Y. Li, J.-X. Pu, H.-D. Sun

DOI: 10.1021/np5005196

CrossRef

[	NS	]	Isodon tenuifolius
[	mp	]	223 - 225 ℃
[	bp	]
[	α	] D	- 40   [ CHCl3/MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Terpenes

Bistenuifolin A

C52H68O18 = 980

J. Nat. Prod. 2014, 77, 2444

J.-H. Yang, W.-G. Wang, X. Du, F. He, H.-B. Zhang, X.-N. Li, Y. Li, J.-X. Pu, H.-D. Sun

DOI: 10.1021/np5005196

CrossRef

[	NS	]	Isodon tenuifolius
[	mp	]	256 - 257 ℃
[	bp	]
[	α	] D	- 27   [ acetone ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Terpenes

Bistenuifolin B

C52H68O18 = 980

J. Nat. Prod. 2014, 77, 2444

J.-H. Yang, W.-G. Wang, X. Du, F. He, H.-B. Zhang, X.-N. Li, Y. Li, J.-X. Pu, H.-D. Sun

DOI: 10.1021/np5005196

CrossRef

[	NS	]	Isodon tenuifolius
[	mp	]
[	bp	]
[	α	] D	- 32   [ acetone ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	cytotoxicity

Alkaloids

Sorazinone A

C11H8N2O2 = 200

J. Nat. Prod. 2014, 77, 2545

R. Jansen, S. Sood, K. I. Mohr, B. Kunze, H. Irschik, M. Stadler, R. Müller

DOI: 10.1021/np500632c

CrossRef

[	NS	]	Nannocystis pusilla
[	mp	]
[	bp	]
[	α	] D
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Alkaloids

Nannozinone A

C15H16N2O = 240

J. Nat. Prod. 2014, 77, 2545

R. Jansen, S. Sood, K. I. Mohr, B. Kunze, H. Irschik, M. Stadler, R. Müller

DOI: 10.1021/np500632c

CrossRef

[	NS	]	Nannocystis pusilla
[	mp	]
[	bp	]
[	α	] D
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	antibacterial and antifungal activity

Alkaloids

Nannozinone B

C16H14N2O2 = 266

J. Nat. Prod. 2014, 77, 2545

R. Jansen, S. Sood, K. I. Mohr, B. Kunze, H. Irschik, M. Stadler, R. Müller

DOI: 10.1021/np500632c

CrossRef

[	NS	]	Nannocystis pusilla
[	mp	]
[	bp	]
[	α	] D
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	growth inhibit activity

Alkaloids

Sorazinone B

C19H18N2O = 290

J. Nat. Prod. 2014, 77, 2545

R. Jansen, S. Sood, K. I. Mohr, B. Kunze, H. Irschik, M. Stadler, R. Müller

DOI: 10.1021/np500632c

CrossRef

[	NS	]	Nannocystis pusilla
[	mp	]
[	bp	]
[	α	] D
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Alkaloids

Tacamonine-N-oxide

C19H22N2O2 = 310

J. Nat. Prod. 2014, 77, 2504

D. S.-Y. Sim, K.-W. Chong, C.-E Nge, Y.-Y. Low, K.-S. Sim, T.-S. Kam

DOI: 10.1021/np500589u

CrossRef

[	NS	]	Tabernaemontana
[	mp	]
[	bp	]
[	α	] D	+ 25   [ CHCl3 ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Alkaloids

Vobasidine B

C21H24N2O3 = 352

J. Nat. Prod. 2014, 77, 2504

D. S.-Y. Sim, K.-W. Chong, C.-E Nge, Y.-Y. Low, K.-S. Sim, T.-S. Kam

DOI: 10.1021/np500589u

CrossRef

[	NS	]	Tabernaemontana
[	mp	]
[	bp	]
[	α	] D	- 142   [ CHCl3 ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	cytotoxicity

Alkaloids

Vobasidine C

C21H26N2O3 = 354

J. Nat. Prod. 2014, 77, 2504

D. S.-Y. Sim, K.-W. Chong, C.-E Nge, Y.-Y. Low, K.-S. Sim, T.-S. Kam

DOI: 10.1021/np500589u

CrossRef

[	NS	]	Tabernaemontana
[	mp	]
[	bp	]
[	α	] D	- 117   [ CHCl3 ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	cytotoxicity

Alkaloids

Vobasidine D

C21H22N2O4 = 366

J. Nat. Prod. 2014, 77, 2504

D. S.-Y. Sim, K.-W. Chong, C.-E Nge, Y.-Y. Low, K.-S. Sim, T.-S. Kam

DOI: 10.1021/np500589u

CrossRef

[	NS	]	Tabernaemontana
[	mp	]
[	bp	]
[	α	] D	- 70   [ CHCl3 ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Alkaloids

Vobasidine A

C21H24N2O4 = 368

J. Nat. Prod. 2014, 77, 2504

D. S.-Y. Sim, K.-W. Chong, C.-E Nge, Y.-Y. Low, K.-S. Sim, T.-S. Kam

DOI: 10.1021/np500589u

CrossRef

[	NS	]	Tabernaemontana
[	mp	]
[	bp	]
[	α	] D	- 35   [ CHCl3 ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	cytotoxicity

Alkaloids

Tacamine-N-oxide

C21H26N2O4 = 370

J. Nat. Prod. 2014, 77, 2504

D. S.-Y. Sim, K.-W. Chong, C.-E Nge, Y.-Y. Low, K.-S. Sim, T.-S. Kam

DOI: 10.1021/np500589u

CrossRef

[	NS	]	Tabernaemontana
[	mp	]
[	bp	]
[	α	] D	- 6   [ CHCl3 ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]

Alkaloids

Plakinamine N

C29H48N2 = 424

J. Nat. Prod. 2014, 77, 2475

S. N. Sunassee, T. Ransom, C. J. Henrich, J. A. Beutler, D. G. Covell, J. B. McMahon, K. R. Gustafson

DOI: 10.1021/np500556t

CrossRef

[	NS	]	Corticium niger
[	mp	]
[	bp	]
[	α	] D	+ 8.8   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	growth inhibit activity

Alkaloids

Pyrrolocin B

C26H37NO5 = 443

J. Nat. Prod. 2014, 77, 2537

R. C. Jadulco, M. Koch, T. B. Kakule, E. W. Schmidt, A. Orendt, H. He, J. E. Janso, G. T. Carter, E. C. Larson, C. Pond, T. K. Matainaho, L. R. Barrows

DOI: 10.1021/np500617u

CrossRef

[	NS	]	NRRL 50135
[	mp	]
[	bp	]
[	α	] D	- 150   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	antimycobacterial activity

Alkaloids

Pyrrolocin C

C26H37NO5 = 443

J. Nat. Prod. 2014, 77, 2537

R. C. Jadulco, M. Koch, T. B. Kakule, E. W. Schmidt, A. Orendt, H. He, J. E. Janso, G. T. Carter, E. C. Larson, C. Pond, T. K. Matainaho, L. R. Barrows

DOI: 10.1021/np500617u

CrossRef

[	NS	]	NRRL 50135
[	mp	]
[	bp	]
[	α	] D	+ 130   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	antimycobacterial activity

Alkaloids

Taipinisine

C29H32N4O = 452

J. Nat. Prod. 2014, 77, 2504

D. S.-Y. Sim, K.-W. Chong, C.-E Nge, Y.-Y. Low, K.-S. Sim, T.-S. Kam

DOI: 10.1021/np500589u

CrossRef

[	NS	]	Tabernaemontana
[	mp	]
[	bp	]
[	α	] D	- 29   [ CHCl3 ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	cytotoxicity

Alkaloids

Pyrrolocin A

C27H39NO5 = 457

J. Nat. Prod. 2014, 77, 2537

R. C. Jadulco, M. Koch, T. B. Kakule, E. W. Schmidt, A. Orendt, H. He, J. E. Janso, G. T. Carter, E. C. Larson, C. Pond, T. K. Matainaho, L. R. Barrows

DOI: 10.1021/np500617u

CrossRef

[	NS	]	NRRL 50135
[	mp	]
[	bp	]
[	α	] D	+ 56.1   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	antimycobacterial activity

Alkaloids

Plakinamine O

C31H50N2O2 = 482

J. Nat. Prod. 2014, 77, 2475

S. N. Sunassee, T. Ransom, C. J. Henrich, J. A. Beutler, D. G. Covell, J. B. McMahon, K. R. Gustafson

DOI: 10.1021/np500556t

CrossRef

[	NS	]	Corticium niger
[	mp	]
[	bp	]
[	α	] D	+ 17.5   [ MeOH ]
[	Ph	]	uv Hnmr Cnmr ir Xray mass cd syn
[	act	]	growth inhibit activity

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