Natural Products with Heterocyclic Ring System

Structure

New Heterocyclic Natural Products

Updated: 26 June, 2015

This journal will list the new natural products with a heterocyclic ring system, collected from current chemical literature, whose structure has been established.

19 data found. 1 - 19 listed
Polyketides

Pyrenocine N

C10H12O4 = 196
J. Antibiot. 2014, 67, 791
Z. Yang, L. Bao, Y. Yin, G. Ding, M. Ge, D. Chen, X. Qian
DOI: 10.1038/ja.2014.59
CrossRef
[ NS ] Colletotrichum species HCCB03289
[ mp ]
[ bp ]
[ α ] D + 28.2   [ MeOH ]
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ]
Polyketides

Pyrenocine O

C10H12O4 = 196
J. Antibiot. 2014, 67, 791
Z. Yang, L. Bao, Y. Yin, G. Ding, M. Ge, D. Chen, X. Qian
DOI: 10.1038/ja.2014.59
CrossRef
[ NS ] Colletotrichum species HCCB03289
[ mp ]
[ bp ]
[ α ] D + 63.0   [ MeOH ]
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ]
Polyketides

Aspergillusol A

C12H12O5 = 236
J. Nat. Prod. 2014, 77, 2375
V. Rukachaisirikul, N. Rungsaiwattana, S. Klaiklay, S. Phongpaichit, K. Borwornwiriyapan, J. Sakayaroj
DOI: 10.1021/np500324b
CrossRef
[ NS ] Aspergillus species PSU-RSPG185
[ mp ]
[ bp ]
[ α ] D - 4.6   [ MeOH ]
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ]
Polyketides

Aspergillusol B

C12H12O5 = 236
J. Nat. Prod. 2014, 77, 2375
V. Rukachaisirikul, N. Rungsaiwattana, S. Klaiklay, S. Phongpaichit, K. Borwornwiriyapan, J. Sakayaroj
DOI: 10.1021/np500324b
CrossRef
[ NS ] Aspergillus species PSU-RSPG185
[ mp ]
[ bp ]
[ α ] D
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ]
Polyketides

No Name

C12H14O5 = 238
Tetrahedron Lett. 2014, 55, 6530
D.-B. Hu, W.-X. Li, Z.-Z. Zhao, T. Feng, R.-H. Yin, Z.-H. Li, J.-K. Liu, H.-J. Zhu
DOI: 10.1016/j.tetlet.2014.09.132
CrossRef
[ NS ] Junghuhnianitida
[ mp ]
[ bp ]
[ α ] D – 8.3   [ MeOH ]
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ]
Polyketides

No Name

C13H16O5 = 252
Tetrahedron Lett. 2014, 55, 6530
D.-B. Hu, W.-X. Li, Z.-Z. Zhao, T. Feng, R.-H. Yin, Z.-H. Li, J.-K. Liu, H.-J. Zhu
DOI: 10.1016/j.tetlet.2014.09.132
CrossRef
[ NS ] Junghuhnianitida
[ mp ]
[ bp ]
[ α ] D – 7.6   [ MeOH ]
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ]
Polyketides

Cryptolactone A1

C18H30O4 = 310
J. Nat. Prod. 2014, 77, 2459
M. Horikawa, M. Inai, Y. Oguri, E. Kuroda, M. Tanaka, S. Suzuki, T. Ito, S Takahashi, H. Kaku, T. Tsunoda
DOI: 10.1021/np500542x
CrossRef
[ NS ] Cryptomyzus species
[ mp ]
[ bp ]
[ α ] D - 53.5   [ CHCl3 ]
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ] cytotoxicity
Polyketides

Cryptolactone A2

C18H30O4 = 310
J. Nat. Prod. 2014, 77, 2459
M. Horikawa, M. Inai, Y. Oguri, E. Kuroda, M. Tanaka, S. Suzuki, T. Ito, S Takahashi, H. Kaku, T. Tsunoda
DOI: 10.1021/np500542x
CrossRef
[ NS ] Cryptomyzus species
[ mp ]
[ bp ]
[ α ] D - 44.1   [ CHCl3 ]
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ] cytotoxicity
Polyketides

Cryptolactone B1

C20H34O4 = 338
J. Nat. Prod. 2014, 77, 2459
M. Horikawa, M. Inai, Y. Oguri, E. Kuroda, M. Tanaka, S. Suzuki, T. Ito, S Takahashi, H. Kaku, T. Tsunoda
DOI: 10.1021/np500542x
CrossRef
[ NS ] Cryptomyzus species
[ mp ]
[ bp ]
[ α ] D - 46.1   [ CHCl3 ]
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ] cytotoxicity
Polyketides

Cryptolactone B2

C20H34O4 = 338
J. Nat. Prod. 2014, 77, 2459
M. Horikawa, M. Inai, Y. Oguri, E. Kuroda, M. Tanaka, S. Suzuki, T. Ito, S Takahashi, H. Kaku, T. Tsunoda
DOI: 10.1021/np500542x
CrossRef
[ NS ] Cryptomyzus species
[ mp ]
[ bp ]
[ α ] D
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ] cytotoxicity
Polyketides

Borrelidin B

C28H47NO6 = 493
J. Nat. Prod. 2014, 77, 2570
C. J. Schulze, W. M. Bray, F. Loganzo, M.-H. Lam, T. Szal, A. Villalobos, F. E. Koehn, R. G. Linington
DOI: 10.1021/np500727g
CrossRef
[ NS ] Streptomyces species
[ mp ]
[ bp ]
[ α ] D + 26.2   [ MeOH ]
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ] growth inhibit activity
Polyketides

Coriapentocin A

C35H64O8 = 612
Helv. Chim. Acta 2014, 97, 1469
T. da C. Alves, M. R. S. Gonçalves, F. C. S. Correia, V. C. da Silva, P. T. de Sousa Jr., M. G. de Carvalho, R. Braz-Filho, E. L. Dall’Oglio
DOI: 10.1002/hlca.201400034
CrossRef




[ NS ] Annona coriacea
[ mp ]
[ bp ]
[ α ] D
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ]
Polyketides

Coriapentocin B

C35H64O8 = 612
Helv. Chim. Acta 2014, 97, 1469
T. da C. Alves, M. R. S. Gonçalves, F. C. S. Correia, V. C. da Silva, P. T. de Sousa Jr., M. G. de Carvalho, R. Braz-Filho, E. L. Dall’Oglio
DOI: 10.1002/hlca.201400034
CrossRef




[ NS ] Annona coriacea
[ mp ]
[ bp ]
[ α ] D
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ]
Polyketides

Azaspiracid-33

C41H65NO9 = 715
J. Nat. Prod. 2014, 77, 2465
J. Kilcoyne, C. Nulty, T. Jauffrais, P. McCarron, F. Herve, B. Foley, F. Rise, S. Crain, A. L. Wilkins, M. J. Twiner, P. Hess, C. O. Miles
DOI: 10.1021/np500555k
CrossRef




[ NS ] Azadinium spinosum
[ mp ]
[ bp ]
[ α ] D
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ] cytotoxicity
Polyketides

Azaspiracid-34

C45H69NO12 = 815
J. Nat. Prod. 2014, 77, 2465
J. Kilcoyne, C. Nulty, T. Jauffrais, P. McCarron, F. Herve, B. Foley, F. Rise, S. Crain, A. L. Wilkins, M. J. Twiner, P. Hess, C. O. Miles
DOI: 10.1021/np500555k
CrossRef
[ NS ] Azadinium spinosum
[ mp ]
[ bp ]
[ α ] D
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ] cytotoxicity
Polyketides

Brevisulcatic Acid-4

C49H70O15 = 898
Org. Lett. 2014, 16, 5850
R. Suzuki, R. Irie, Y. Harntaweesup, K. Tachibana, P. T. Holland, D. T. Harwood, F. Shi, V. Beuzenberg, Y. Itoh, S. Pascal, P. J. B. Edwards, M. Satake
DOI: 10.1021/ol502700h
CrossRef
[ NS ] Karenia brevisulcata
[ mp ]
[ bp ]
[ α ] D + 3.0   [ MeOH ]
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ]
Polyketides

Brevisulcatic Acid-1

C49H72O16 = 916
Org. Lett. 2014, 16, 5850
R. Suzuki, R. Irie, Y. Harntaweesup, K. Tachibana, P. T. Holland, D. T. Harwood, F. Shi, V. Beuzenberg, Y. Itoh, S. Pascal, P. J. B. Edwards, M. Satake
DOI: 10.1021/ol502700h
CrossRef
[ NS ] Karenia brevisulcata
[ mp ]
[ bp ]
[ α ] D
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ]
Polyketides

Amdigenol G

C60H101O25NaS = 1276
Tetrahedron Lett. 2014, 55, 6319
T. Inuzuka, K. Yamada, D. Uemura
DOI: 10.1016/j.tetlet.2014.09.094
CrossRef




[ NS ] Amphidinium species
[ mp ]
[ bp ]
[ α ] D – 5.3   [ MeOH ]
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ] inhibitory activity against N-type Ca2+ channel-opening
Polyketides

Amdigenol E

C82H137O37NaS = 1768
Tetrahedron Lett. 2014, 55, 6319
T. Inuzuka, K. Yamada, D. Uemura
DOI: 10.1016/j.tetlet.2014.09.094
CrossRef




[ NS ] Amphidinium species
[ mp ]
[ bp ]
[ α ] D – 6.4   [ MeOH ]
[ Ph ]
uv Hnmr Cnmr ir
Xray mass cd syn
[ act ] inhibitory activity against N-type Ca2+ channel-opening
19 data found. 1 - 19 listed