Regular Issue

Vol. 24, No. 7, 1986

33 data found. 31 - 33 listedFirst Previous
Paper | Regular issue | Vol 24, No. 7, 1986, pp. 2007 - 2014
Published online:
DOI: 10.3987/R-1986-07-2007
Dimerization of 2,2-Disubstituted 1,3-Dicarbonyl Compounds. A Synthesis of 2,4,6,8-Tetraoxa-adamantane Derivatives

Sadao Tsuboi, Tsuyoshi Ono, and Akira Takeda*

*Faculty of Pharmaceutical Sciences, Okayama University, 1-1-1 Tsushima-naka, Okayama 700-8530, Japan

Abstract

Treatment of 2,2-dimethyl-3-oxobutanal and 2,2-dimethyl-3-oxopentanal with sulfuryl chloride gave 1,3,9,9,10,10-hexamethyl-2,4,6,8-tetraoxa-adamantane and 1,3-diethyl-9,9,10,10-tetramethyl-2,4,6,8-tetraoxa-adamantane in 100% and 70% yields, respectively. Thionyl chloride and hydrogen chloride also catalyzed the dimerization.

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Paper | Regular issue | Vol 24, No. 7, 1986, pp. 2015 - 2022
Published online:
DOI: 10.3987/R-1986-07-2015
Synthesis of 3,5-trans-3-methoxycarbonyl-1-carbapenam from Methyl (±)-Pyroglutamate

Tatsuo Nagasaka,* Atsuhiko Tsukada, and Fumiko Hamaguchi

*School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan

Abstract

Synthesis of 3,5-trans-3-methoxycarbonyl-1-carbapenam in six steps from methyl (±)-pyroglutamate is described.

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Review | Regular issue | Vol 24, No. 7, 1986, pp. 2023 - 2048
Published online:
DOI: 10.3987/R-1986-07-2023
Utiliry of Cyanoacetamide and Cyanothioacetamide in Heterocyclic Synthesis

Fathy Mohamed Abdel-Galil, Sherif Mourad Sherif,* and Mohamed Hilmy Elnagdi

*Department of Chemistry, Faculty of Science, University of Cairo, Giza, Egypt

Abstract

The preparation and utility of cyanoacetamide and cyanothioacetamide in heterocyclic synthesis are reviewed.

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33 data found. 31 - 33 listedFirst Previous