Regular Issue

Vol. 24, No. 3, 1986

38 data found. 1 - 30 listed Next Last
Communication | Regular issue | Vol 24, No. 3, 1986, pp. 571 - 574
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DOI: 10.3987/R-1986-03-0571
Efficient Synthesis of (±)-Emetine and (±)-Protoemetinol by the Stereoselective Intramolecular Michael Reaction

Yoshiro Hirai, Atsushi Hagiwara, and TakaoYamazaki*

*Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama, Toyama 930-0194, Japan


The intramolecular Michael Reaction of 8 and 12 gave stereoselectively 9 and 13, which were converted to the emetine precursor (11) and (±)-protoemetinol (2).

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Communication | Regular issue | Vol 24, No. 3, 1986, pp. 575 - 578
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DOI: 10.3987/R-1986-03-0575
Pyrrolothioenpyrimidines II. Synthesis of 4-Aminopyrrolo[1,2-a]thieno[3,2-e] (and [2,3-e])pyrimidines

Sylvain Rault, Yamien Effi, Jean-Charles Lancelot, and Max Robba*

*Laboratoire de Chimie Thérapeutique, U. F. R. des Sciences Pharmaceutiques, Université de Caen, 1, rue Vaubénard, 14032 Caen Cedex, France


Cyclization of the appropriate cyanothienylpyrrolylcarboxylic acid azides in boiling ortho-dichlorobenzene conducted to the corresponding aminopyrrolothienopyrimidines.

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Communication | Regular issue | Vol 24, No. 3, 1986, pp. 579 - 582
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DOI: 10.3987/R-1986-03-0579
The Reactions of 1-Methylpyrrole and 1-Phenylpyrrole with 3,4,5,6-Tetrachloro-1,2-benzoquinone and 1,2-Naphthoquinone

Katsuhiro Saito* and Yoichi Horie

*Faculty of Engineering, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya 466-8555, Japan


The reactions of pyrrole derivatives with 3,4,5,6-tetrachloro-1,2-benzoquinone and 1,2-naphthoquinone afforded the keto-enol-type and the hydroquinone-type substitution products, respectively, via the nucleophilic attack of the pyrrole derivatives on the o-quinone derivatives.

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Communication | Regular issue | Vol 24, No. 3, 1986, pp. 583 - 587
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DOI: 10.3987/R-1986-03-0583
Intramolecular Cyclisation Using Methyl(bismethylthio)sulphonium Salts. Part 4. Synthesis of Functionalized Indoles and Dihydroindoles

Giuseppe Capozzi,* Rosaria Ottana’, and Giovanni Romeo

*CNR, Centro di Studio Sulla Chimica e la Struttura dei Composti Eterociclici e lolo Applicazioni, c/o Dipartimento di Chimica Organica "Ugo Schiff", Università di Firenze, Via Gino Capponi 9, I-50121 Firenze, Italy


The 3-methyl-2-methylthio-1-p-tolylsulphonylindole (7) and the 2-(methylthiomethyl)-1-p-tolylsulphonyldihydroindole (8) were synthesized in one pot reactions of methyl(bismethylthio)sulphonium hexachloroantimonate (1) with 2-(2-propenyl)-N-tosylaniline (5) and 2-allyl-N-tosylaniline (6) respectively.

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Communication | Regular issue | Vol 24, No. 3, 1986, pp. 589 - 592
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DOI: 10.3987/R-1986-03-0589
New Methods and Reagents in Organic Synthesis. 59. Lithium Trimethylsilydiazomethane: A New Synthon for the Preparation of 5-Substituted 1,2,3-Thiadiazoles

Toyohiko Aoyama,* Yuji Iwamoto, and Takayuki Shioiri

*Faculty of Pharmaceutical Sciences, Nagoya City University, Tanabe-dori, Mizuho-ku, Nagoya 467-8603, Japan


Lithium trimethylsilyldiazomethane smoothly reacts with thionoesters, dithioesters, and carbon disulfide to give 5-substituted 1,2,3-thiadiazoles.

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Communication | Regular issue | Vol 24, No. 3, 1986, pp. 593 - 599
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DOI: 10.3987/R-1986-03-0593
Trifluoropyruvic Acid Hydrate in Heterocyclic Synthesis, Part II.: Synthesis of Trifluomethylated Benzoxazine, Benzothiazine, and Benzoxazole Derivatives

Mohamed El-said Mustafa, Akio Takaoka, and Nobuo Ishikawa*

*Department of Chemical Technology, Faculty of Engineering, Tokyo Institute of Technology, 2-12-1,Oh-Okayama, Meguro-ku, Tokyo 152-8552, Japan


Synthesis of 2-hydroxy-2-trifluoromethyl-2H-1,4-benzoxazin-3(4H)-one derivatives, 3-trifluoromethyl-1,4-benzoxazin-2-one derivatives, 2,3-dihydro-2-trifluoromethylbenzoxazole derivatives and 2-hydroxy-2-trifluoromethyl-2H-1,4-benzothiazin-3(4H)-one, by the reaction of trifluoropyruvic acid hydrate with 4-substituted 2-aminophenols and 2-aminothiophenol, respectively, is reported. The effect of the substituent, in the aminophenol ring, on the ratio of the formed isomers of benzoxazine is also investigated.

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Communication | Regular issue | Vol 24, No. 3, 1986, pp. 601 - 605
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DOI: 10.3987/R-1986-03-0601
Protosappanin B, a New Dibenzoxocin Derivative from Sappan lignum

Masahiro Nagai* and Seiji Nagumo

*Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501, Japan


A new dibenzoxocin derivative, named protosappanin B, C16H16O6, white amorphous powder, [α]D15 -11.4° (MeOH) was isolated from the heart-wood of Caesalpinia sappan L. (Leguminosae). It yielded a trimethyl ether (2) on methylation with diazomethane, a tetraacetate (5) and a pentaacetate (6) on acetylation, and sappanin (4) on alkali fusion. Protosappanin B (1) was chemically correlated with trimethyl ether (3) of protosappanin A (7). On the basis of the chemical and spectroscopic evidence, the chemical structure of 1 was established as 3,7,10,11-tetrahydroxy-7,8-dihydro-7(6H)-dibenz[b,d]oxocinmethanol. The cd spectrum of 1 indicated that its biphenyl system preferentially takes S configuration, from which S configuration was tentatively assigned to C-7 of 1.

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Communication | Regular issue | Vol 24, No. 3, 1986, pp. 607 - 610
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DOI: 10.3987/R-1986-03-0607
Medelline, First Bisbenzylisoquinoline Alkaloid with a Methylenedioxy Bridge

Diego Cortes, Jairo Saez, Reynald Hocquemiller, André Cavé,* and Adrien Cavé

*Laboratoire de Chimie Therapeutique, Faculte de Pharmacie, Université Paris XI, 5, rue Jean-Baptiste Clément, 92290 Chatenay-Malabry Cedex, France


High resolution MS and 1H-NMR studies indicate that medelline, a minor alkaloid isolated from the bark of Pseudoxandra aff. lucida, is the first known example of a bisbenzylisoquinoline alkaloid with a methylenedioxy bridge joining both halves of the molecule. Medelline is probably biosynthesized via intramolecular condensation of the accompanying major bisbenzylisoquinoline alkaloid, antioquine.

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Communication | Regular issue | Vol 24, No. 3, 1986, pp. 611 - 615
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DOI: 10.3987/R-1986-03-0611
Intramolecular Dipolar Cycloaddition Reactions of C-Aryl Oxaziridines

Albert Padwa* and Konrad F. Koehler

*Department of Chemistry, Emory University, 1521 Pierce Drive Atlanta, Georgia 30322, U.S.A.


Thermolysis of several C-aryl oxaziridines containing Π-unsaturation in close proximity to the three-membered ring results in the formation of intramolecular dipolar cycloadducts derived from transient nitrone intermediates.

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Communication | Regular issue | Vol 24, No. 3, 1986, pp. 617 - 620
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DOI: 10.3987/R-1986-03-0617
Phosphono Nucleoside. 1. Synthesis of 2,3’-Anhydro-1’-deoxy-1’-phosphono-1-β-D-fructofuranosyl Uracil

Toshio Tatsuoka,* Kayoko Imao, and Kenji Suzuki

*Suntory Institute for Biochemical Research, Suntory Institute for Biochemical Research, 1-1-1, Wakayamadai, Shimamotocho, Mishimagun, Osaka 618-0024, Japan


New phosphono nucleosides, phosphono methyl derivatives of anhydro nucleoside substituted at C-1’, were synthesized starting from 2,3’-anhydro-1-β-D-fructofuranosyl uracil.

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Communication | Regular issue | Vol 24, No. 3, 1986, pp. 621 - 624
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DOI: 10.3987/R-1986-03-0621
A Diadtereoselective Synthesis of threo 2-(α-Hydroxyalkyl)piperdines via Oxacarbamoylinium Ion-(Z)-vinylsilane Cyclization

Shinzo Kano,* Tsutomu Yokomatsu, Yoko Yuasa, and Shiroshi Shibuya

*School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan


Reduction of 5-alkyl-N-(Z-4-silyl-3-butenyl)oxazolidine-2,4-diones (5a,b) with NaBH4, followed by cyclization with TiCl4 afforded the corresponding 1,8a-trans-1-alkyl-1,5,6,8a-tetrahydro-3H-oxazolo[3,4-a]pyridines (9a,b), respectively, with high diastereoselectivity. Catalytic hydrogenation of 9a, followed by alkaline hydrolysis gave threo 2-(α-hydroxyethyl)piperidine (12a). In a similar fashion, threo 2-(α-hydroxypropyl)piperidine (12b), (±)-β-conhydrine, was obtained from 9b.

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Communication | Regular issue | Vol 24, No. 3, 1986, pp. 625 - 628
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DOI: 10.3987/R-1986-03-0625
Synthesis of N6-(2-Oxopyrrolidin-5-yl)adenosine Derivatives

Yoshiyuki Kosugi,* Tatsuo Nagasaka, Fumiko Hamaguchi, and Sadao Ohki

*School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan


A convenient method for introducing a pyrrolidinyl moiety into adenosine N6-position by utilizing the acyliminium activity of ω-alkoxylactams is described. Condensation of 5-alkoxy-2-pyrrolidinones (3a-f) and adenosine triacetate followed by deacetylation gave N6-(2-oxopyrrolidin-5-yl)adenosines (6a-f) in good yields.

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Communication | Regular issue | Vol 24, No. 3, 1986, pp. 629 - 632
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DOI: 10.3987/R-1986-03-0629
Sequential Intramolecular Diels-Alder Reaction and Intermolecular 1,3-Dipolar Cycloaddition Reaction: One-pot [6.6.5]Annelation Reaction Leading to the Formation of Polyazasteroid Type Skeletons

Otohiko Tsuge,* Kazunori Ueno, and Shuji Kanemasa

*Research Institute of Industrial Science, Faculty of Engineering, Kyushu University, 6-1, Kasuga-koen, Kasuga 816-8580, Japan


The reaction of methyl o-(2-furylmethyloxy)- and o-[N-ethyl-N-2-(furylmethyl)amino]cinnamate with phenyl azide provided the one-pot [6.6.5]annelation reaction leading to the formation of polyaza-steroid type skeletons through an intramolecular Diels-Alder reaction, followed by an intermolecular 1,3-dipolar cycloaddition reaction.

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Communication | Regular issue | Vol 24, No. 3, 1986, pp. 633 - 636
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DOI: 10.3987/R-1986-03-0633
■ Preparation of O-Protected (2S,3S)-1,2-Epoxy-3-butanols. Enantioselective Syntheses of (—)-Rhodinose and (+)-Epimuscarine Iodide

Susumi Hatakeyama, Kuniya Sakurai, and Seiichi Takano*

*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan


Reductive cleavage of (S,S)-1,2-3,4-diepoxybutane with lithium triethylborohydride, followed by protection gave O-protected (2S,3S)-1,2-epoxy-3-butanols, which were employed in chiral syntheses of (-)-rhodinose and (+)-epimuscarine iodide.

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Communication | Regular issue | Vol 24, No. 3, 1986, pp. 637 - 640
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DOI: 10.3987/R-1986-03-0637
Preparation of Naturally Occurring α-Terthiophenes (2,2’:5’,2’’-Terthiophenes)

Juzo Nakayama,* Yoichi Nakamura, Takayuki Tajiri, and Masamatsu Hoshino

*Department of Chemistry, Faculty of Science, Saitama University, Saitama, Saitama 338-8570, Japan


A series of naturally occurring α-terthiophenes (2,2’:5’,2”-terthiophenes) were prepared using readily accessible bis[2-oxo-2-(2-thienyl)ethyl] sulfide as the starting material.

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Communication | Regular issue | Vol 24, No. 3, 1986, pp. 641 - 645
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DOI: 10.3987/R-1986-03-0641
An Enantioselective Synthesis of (—)-6-Aza-6-carbethoxy-2-oxabicyclo[3.3.0]octan-3-one from S-(—)-Malic Acid

Kozo Shishido, Yuko Sukegawa, Keiichiro Fukumoto,* and Tetsuji Kametani

*Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan


An enantioselective synthesis of the title compound, a precursor for the Geissman lactone, from S-(-)-malic acid is described. The synthesis features the diastereoselective intramolecular Michael reaction of the carbamate (3).

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Report | Regular issue | Vol 24, No. 3, 1986, pp. 647 - 650
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DOI: 10.3987/R-1986-03-0647
Synthesis and Crystal Structure of Dimethyl N,N’-Diethoxycarbonyl-3,4,7,8-tetrahydro-4,7-phenanthroline-3,8-diphosphonate

Isao Takeuchi, Yasuhiro Shibata, Yoshiki Hamada,* and Masaru Kido

*Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tenpaku, Nagoya 468-8503, Japan


Reaction was performed of 4,7-phenanthroline with trimethyl phosphite and ethyl chlorocarbonate in the presence of sodium iodide in acetonitrile as a solvent, to yield dimethyl N,N’-diethoxycarbonyl-3,4,7,8-tetrahydro-4,7-phenanthroline-3,8-diphosphonate (3) and 3,10-diphosphonate (4). 3,8-Diphosphonate (3) was processed in the column chromatogram and was separated into isomers 3a and 3b whose structures were determined by X-ray analysis.

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Report | Regular issue | Vol 24, No. 3, 1986, pp. 651 - 654
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DOI: 10.3987/R-1986-03-0651
Nitrogen Assisted Enol Ether Formation

Mauri Lounasmaa* and Arto Tolvanen

*Laboratory for Organic and Bioorganic Chemistry, Technical University of Helsinki, P.O. Box 6100, FIN-02150 HUT, Espoo 15, Finland


A nitrogen assisted enol ether formation via cyclic acetal ring opening is described.

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Report | Regular issue | Vol 24, No. 3, 1986, pp. 655 - 658
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DOI: 10.3987/R-1986-03-0655
A Facile Synthesis of Functionalized Novel Monocyclic trans-β-Lactams

Dilip Kumar Dutta, Romesh Chandra Boruah, and Jagir Singh Sandhu*

*Division of Natural Products Chemistry, Regional Reseach Labratory (CSIR), Jorhat-6, Assam, India


Treatment of copper acetylide (1) with aroyl-N-aryl nitrone (2) afforded a novel class of 4-aroyl functionalized monocyclic trans-β-lactam (3). Oxidative N-dearylation of 3e with cerric ammonium nitrite (CAN) gave N-unsubstituted trans-β-lactam (4) in good yield.

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Report | Regular issue | Vol 24, No. 3, 1986, pp. 659 - 664
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DOI: 10.3987/R-1986-03-0659
Radical Mechanism in the Photoreaction of Organic N-Oxides: Some Paradiazine N,N-Dioxides

Lin Shukun and Wang Hanqing*

*Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, China


Based on the e.s.r. identified nitroxyl radicals 4,5, and 6 produced in organic solvent, a radical mechanism in the photoreaction of some paradiazine N,N-dioxides was suggested. The intermediate radicals 8 were produced , in the photoreduction process such as deoxygenation and hydrogen abstraction, from either triplet excited state or from diradicals 7.

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Report | Regular issue | Vol 24, No. 3, 1986, pp. 665 - 668
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DOI: 10.3987/R-1986-03-0665
Reaction of 3a,4-Dihydrophthalides with Acetylenic Dienophiles

Michihiko Noguchi,* Shinji Kakimoto, and Shoji Kajigaeshi

*Department of Applied Chemistry, Faculty of Engineering, Yamaguchi University, 2-16-1 Tokiwadai, Ube, Yamaguchi 755-8611, Japan


The tricyclo[2.2.2]octa-2,5-diene-4,7-carbolactones, the initially-formed Diels-Alder adducts from 3a,4-dihydrophthalides and acetylenic dienophiles, were so strained that they underwent the retro-Diels-Alder reaction to afford the benzene derivatives in good yields.

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Paper | Regular issue | Vol 24, No. 3, 1986, pp. 669 - 678
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DOI: 10.3987/R-1986-03-0669
Anodic Dimerization of 1,2,3,4-Tetrahydrocabazole and Some of Its Derivatives

James M. Bobbitt,* Paul M. Scola, Chidambar L. Kulkarni, Anthony J. DeNicola, Jr., and Thomas T. -t. Chou

*Department of Chemistry, University of Connecticut, Storrs, CT 06269-3060, U.S.A.


The anodic oxidation of 1,2,3,4-tetrahydrocarbazole and two of its derivatives in aqueous acetonitrile at about +0.7 V (vs a standard calomel electrode and using a graphite felt anode) gave dimers having a linkage between carbon 4a of one unit and carbon 7 of the other. The oxidation of 5-methyl-5,6,7,8,9,10-hexahydrocyclohept[b]indole gave a corresponding dimer with a 5a-8’ linkage. This is a correction and an extension of our earlier work.

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Paper | Regular issue | Vol 24, No. 3, 1986, pp. 679 - 686
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DOI: 10.3987/R-1986-03-0679
Synthesis of 2-Mercapto- and 2-Methylthio- Dihydropyrimidine Derivatives by Biguinelli Type Reaction

M. Velpuesta Fernández,* F. J. Herrera, and T. Lupión Cobos

*Departamento de Quimica Organica, Facultad de Ciencias, Universidad de Málaga, Campus de Teations, E-29071 Malaga, Spain


The preparation of 6-(2,2-dimethyl-1,3-dioxolan-4-yl)-4-methyl-5-methoxycarbonyl-2-thio-1,2,3,6-tetrahydropyrimidine (1) and 6-(2,2-dimethyl-1,3-dioxolan-4-yl)-4-methyl-2-methylthio-5-methoxycarbonyl-1,6-dihydropyrimidine (6) by Biguinelli type reaction is described. The products resulting from the acidic hydrolysis are studied.

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Paper | Regular issue | Vol 24, No. 3, 1986, pp. 687 - 696
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DOI: 10.3987/R-1986-03-0687
Dynamic 13C N.M.R. Studies of Electrochemically Formed 4a-N’ and 4a-4a’ Dehydrodimers of 1,2,3,4-Tetrahydrocarbazole

James M. Bobbitt,* Thomas T. -t. Chou, and Thomas K. Leipert

*Department of Chemistry, University of Connecticut, Storrs, CT 06269-3060, U.S.A.


The electrochemical oxidation of 1,2,3,4-tetrahydrocarbazole in strong base (KOCH3 in CH3OH) at a potential of + 0.15 V (vs S.C.E.) on a graphite felt anode produced a series of dehydrodimers having interesting stereochemical and 13C dynamic N.M.R. properties. The 4a-N’ dimer was isolated as a pair of atropisomers due to restricted rotation around a nitrogen-sp3 carbon bond. Meso and dl forms of the 4a-4a’ dimer were also isolated. Low temperature 13C N.M.R. spectra of the 4a-4a’ dimers showed that they represent a unique case of stereochemistry when rotation is restricted. The case corresponds to a situation where the anti conformation around an acyclic sp3-sp3 carbon-carbon bond is forbidden, and only the two gauche forms are present.

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Paper | Regular issue | Vol 24, No. 3, 1986, pp. 697 - 702
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DOI: 10.3987/R-1986-03-0697
Titanium Trichloride Mediated Reduction of Nitrostyrenes

Akira Sera,* Shoji Fukumoto, Takako Yoneda, and Hiroaki Yamada

*Department of Chemistry, Faculty of Science, Kobe University, Nada-Ku, Kobe 6557-8501, Japan


Reactions of substituted nitrostyrenes with aqueous titanium trichloride afforded pyrroles, carbonyl compounds, and oximes. In some instances, divinylamines were produced as well. The reaction mechanism is rationalized taking account of electron transfer to nitroethylenes from Ti(III), followed by protonation, dimerization, cyclization, and hydrolysis.

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Paper | Regular issue | Vol 24, No. 3, 1986, pp. 703 - 709
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DOI: 10.3987/R-1986-03-0703
Bhimberine — A New Indole Alkaloid from Rhazya stricta

Atta-ur-Rahman,* Habib-ur-Rehman, and Sohail Malik

*H. E. J. Postgraduate Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan


A new Corynanthe type indole alkaloid, bhimberine, has been isolated from Rhazya stricta. Its structure has been assigned as (1) on the basis of spectral studies. Its stereochemistry has been determined by a series of NOED measurements and 13C-NMR assignments made by DEPT pulse sequences.

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Paper | Regular issue | Vol 24, No. 3, 1986, pp. 711 - 717
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DOI: 10.3987/R-1986-03-0711
Heterocycles 2: Synthesis of 1-Hydroxycarbazoles and Mukonine Isomers

Desikachari Sowmithran* and Karnam Jayarampillai Rajendra Prasad

*Department of Chemistry, Indian Institute of Technology, Powai, Bombay 400 076, India


Cyclohexan-1’,2’-dione-1’-diazabenzoic acids obtained from diazotised aminobenzoic acids and 2-hydroxymethylenecyclohexanone on cyclization afford 1-oxo-1,2,3,4-tetrahydrocarbazole derivatives. These on esterification followed by aromaisation and methylation gave the Mukonine isomers, 19, 20 and 22.

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Paper | Regular issue | Vol 24, No. 3, 1986, pp. 719 - 732
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DOI: 10.3987/R-1986-03-0719
Synthesis and Structural Study of New Derivatives of 6,8-Diaryl-3-thia-7-azabicyclo[3.3.1]nonane Systems

Emilio F. Llama* and Gregorio G. Trigo

*Departamento de Química Orgánica y Farmacéutica, Facultad de Farmacia, Universidad Complutense de Madrid, Ciudad Universitaria, 28040 Madrid, Spain


The synthesis and structural analysis of new derivatives of the 6,8-diaryil-3-thia-7-azabicyclo[3.3.1]nonane systems were studied. The high reactivity and stereoselectivity presented by this type of system demonstrates the rigid special arrangement acquired by this type of molecule. Nucleophilic attack on the carbonyl group of 6,8-diaryl-3-thia-7-azabicyclo[3.3.1]nonan-9-one (Grignard and Reformatsky reactions) exclusively produce β-isomers, unlike the Bucherer-Bergs reaction which produced a mixture of isomeric hydantoins. The percentage of isomers and the configuration at C-9 was determined by 1H-NMR spectroscopy. An IR study of solid state association in this type of molecule is presented.

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Paper | Regular issue | Vol 24, No. 3, 1986, pp. 733 - 736
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DOI: 10.3987/R-1986-03-0733
Convenient Method for the Synthesis of Some New 2-(2-Carboxystyryl)-5-(2-methoxycarbonylstyryl)furans

Grace Karminski-Zamola,* Miro Bajic, Marina Tkalcic, and Lelja Fiser-Jakic

*Organic Chemistry Department, Faculty of Technology, University of Zagreb, Marulicev trg 20, 41000 Zagreb, Croatia


It is described very convenient method for the synthesis of some 2-(2-carboxystyryl)-5-(2-methoxycarbonylstyryl)furans. The configuration on the both ethene chain is “E”.

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Paper | Regular issue | Vol 24, No. 3, 1986, pp. 737 - 742
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DOI: 10.3987/R-1986-03-0737
Synthesis of Homoadamantano[4,5-d]imidazoles via Photochemical Ring Transformations

Shoji Eguchi,* Koji Asai, and Tadashi Sasaki

*Faculty of Engineering, Nagoya University, Chikusa, Nagoya, Aichi 464-8601, Japan


The irradiation of homoadamantano[4,5-b]-5’,6’-dihydropyrazines afforded homoadamantano[4,5-d]imidazoles via photochemical ring cleavage followed by cyclization and proton transfer.

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38 data found. 1 - 30 listed Next Last